Thinking sweet: the relationship between diabetes and cognitive dysfunctionReview
- Vol.26 N.6 november-december 2010T. Cuklerman-Jaffe1
With the aging of the population the prevalence of two common disorders is
expected to rise: diabetes and dementia. It has been shown that people with
diabetes are approximately 1.5 times more likely to experience cognitive de-
cline and 1.6 more likely to develop frank dementia than people without dia-
betes. This appears to be due to a higher prevalence of both vascular demen-
tia and Alzheimer’s disease. The aim of this review is to describe the
importance of this relationship, the evidence supporting it, possible explana-
tions, and the implications of this relationship for physicians caring for people
T. Cuklerman-Jaffe, MD, MSC
Gertner Institute for Epidemiology and Health Policy Research. Endocrinology Institute.
Sheba Medical Center. Tel Hashomer. Epidemiology Department. Tel-Aviv University (Israel).
Keywordsdementia neonatal diabetes cognitive dysfunction disglycemia