Longitudinal study of the impact of the treatment with insulin infusion in psychological, quality of life, and glycemic control of patient with type 1 diabetes mellitusOriginal Articles
- Vol.26 N.2 Marc-april 2010M.T.Anarte1, M.S. Ruiz de Adana2, M. Carreira, M. Domínguez-López3, A. Machado4, I. González Molero5, F.F. Caballero6, M. de la Higuera7, S. González Romero8, I.Sánchez9, F.J. C.-Soriguer Escofet10
Introduction: Since the DCCT study, many studies have tried to assess dif-
ferent intensive therapies. However, few long-term studies have included psy-
chosocial variables. Objectives: To evaluate psychological and metabolic var-
iables in patients with type 1 diabetes after 2 years of therapy with continuous
subcutaneous insulin infusion (CSII). Materials and methods: Twenty-two
type 1 diabetic patients treated with multiple daily injections were treated with
CSII. An evaluation at 6, 12 and 24 months was performed, using several in-
struments as BDI, DQOL, MHLC and a questionnaire to evaluate fear of hy-
poglycaemia. Acceptable metabolic control was admitted with HbA1c <7.5%.
Statistical analysis was realized using non parametric tests and Pearson’s cor-
relation coefficient. Results: Initially, patients had a mean score for depression
of 9.55 ± 9.12 (mean ± SD). In quality of life, initial values were 92.95 ±
16.15, while the level of HbA1c was 8.45 ± 1.59%. After 2 years of treatment
we found significant improvement in depression (p= 0.018) and quality of life
(p= 0.005) scores and glycemic control (p= 0.003). Trait anxiety and external
locus of control showed a significant correlation, with a strong correlation be-
tween fear of hypoglycemia and the analyzed psychosocial variables. Patients
with bad basal glycemic control improved after 2 years of treatment. Conclu sions: After two years with CSII, type 1 diabetic patients improve significantly
their quality of life, glycemic control and depressive symptoms.
Correspondencia: M.T. Anarte Ortiz. Departamento de Personalidad, Evaluación y Tratamiento Psicológico.
Facultad de Psicología. Universidad de Málaga. Campus de Teatinos. 29071 Málaga.
Correo electrónico: email@example.com
Keywordsanxiety quality of life continuous subcutaneous insulin infusion depression type 1 diabetes mellitus type 2 diabetes mellitus Continuous Subcutaneous Insulin Infusion insulin pump locus of control.