Longitudinal study of the impact of the treatment with insulin infusion in psychological, quality of life, and glycemic control of patient with type 1 diabetes mellitus

Original Articles - Vol.26 N.2  Marc-april 2010
M.T.Anarte¹, M.S. Ruiz de Adana², M. Carreira, M. Domínguez-López³, A. Machado⁴, I. González Molero⁵, F.F. Caballero⁶, M. de la Higuera⁷, S. González Romero⁸, I.Sánchez⁹, F.J. C.-Soriguer Escofet¹⁰

 Author Affiliations

Abstract

Introduction: Since the DCCT study, many studies have tried to assess dif- ferent intensive therapies. However, few long-term studies have included psy- chosocial variables. Objectives: To evaluate psychological and metabolic var- iables in patients with type 1 diabetes after 2 years of therapy with continuous subcutaneous insulin infusion (CSII). Materials and methods: Twenty-two type 1 diabetic patients treated with multiple daily injections were treated with CSII. An evaluation at 6, 12 and 24 months was performed, using several in- struments as BDI, DQOL, MHLC and a questionnaire to evaluate fear of hy- poglycaemia. Acceptable metabolic control was admitted with HbA1c <7.5%. Statistical analysis was realized using non parametric tests and Pearson’s cor- relation coefficient. Results: Initially, patients had a mean score for depression of 9.55 ± 9.12 (mean ± SD). In quality of life, initial values were 92.95 ± 16.15, while the level of HbA1c was 8.45 ± 1.59%. After 2 years of treatment we found significant improvement in depression (p= 0.018) and quality of life (p= 0.005) scores and glycemic control (p= 0.003). Trait anxiety and external locus of control showed a significant correlation, with a strong correlation be- tween fear of hypoglycemia and the analyzed psychosocial variables. Patients with bad basal glycemic control improved after 2 years of treatment. Conclu sions: After two years with CSII, type 1 diabetic patients improve significantly their quality of life, glycemic control and depressive symptoms.

Correspondence

Correspondencia: M.T. Anarte Ortiz. Departamento de Personalidad, Evaluación y Tratamiento Psicológico.
Facultad de Psicología. Universidad de Málaga. Campus de Teatinos. 29071 Málaga.
Correo electrónico: anarte@uma.es

Keywords

anxiety quality of life continuous subcutaneous insulin infusion depression type 1 diabetes mellitus type 2 diabetes mellitus Continuous Subcutaneous Insulin Infusion insulin pump locus of control.

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